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. 2020 Sep 30;10:16154. doi: 10.1038/s41598-020-73123-y

Table 2.

Association between antibiotics, drug resistance patterns and phage susceptibility.

Antibiotics/drug resistance patterns No. of phage susceptible isolates p-values*
Drug resistant Drug susceptible
Antibiotics
Amikacin (AK) 80/123 (65.04%) 27/107 (25.23%)  < 0.001
Ciprofloxacin (CIP) 104/196 (53.06%) 3/34 (8.82%)  < 0.001
Trimethoprim/sulfamethoxazole (SXT) 75/151 (49.67%) 32/79 (40.51%) 0.1859
Cefotaxime (CTX) 96/185 (51.89%) 11/45 (24.44%) 0.0009
Ceftazidime (CAZ) 100/191 (52.35%) 7/39 (17.95%) 0.0001
Cefoperazone/sulbactam (CSL) 38/66 (57.57%) 69/164 (42.07%) 0.0330
Imipenem (IPM) 103/189 (54.49%) 4/41 (9.76%)  < 0.001
Meropenem (MEM) 104/188 (55.32%) 3/42 (7.14%)  < 0.001
Piperacillin/tazobactam (PIP) 101/190 (53.16%) 6/40 (15.00%)  < 0.001
Tetracycline (TE) 89/142 (62.67%) 18/88 (20.45%)  < 0.001
Ceftriaxone (CRO) 101/193(52.33%) 6/37 (16.22%) 0.0001
Cefepime (FEP) 89/170 (52.35%) 18/60 (30.00%) 0.0028
Gentamicin (CN) 83/146 (56.85%) 24/84 (28.57%)  < 0.001
Drug resistance patterns
MDR-AB 105/199 (52.76%) 2/31 (6.45%)  < 0.001
CR-AB 103/192 (53.64%) 4/38 (10.53%)  < 0.001
XDR-AB 20/28 (71.43%) 87/202 (43.07%) 0.0048
Non MDR-AB 2/28 (7.14%) 105/202 (51.98%)  < 0.001

*p-values less than 0.05 were considered as a statistically significant difference (Fisher's exact test). Bold font indicates statistically significant difference between two groups.