Table 2.
Anticancer screening of endophytic fungi extracts on uterine cervical cancer cells (HeLa). The anticancer activity was determined via MTT assay after exposure to metabolite extracts for 48 h.
| Code | HeLa cells |
|---|---|
| IC50 (µg/ml) | |
| N8 | NC |
| N97 | 33.35 |
| N223 | 136.80 |
| N169 | 149.20 |
| N2 | 175.80 |
| N7 | NC |
The IC50 values were determined using GraphPad Prism. ∗p < 0.05, ∗∗p < 0.001, ∗∗∗p < 0.0001 significantly different from control. Samples were compared using One-Way ANOVA and Tukey comparison of all pairs of columns. IC50: extract concentration required to reduce HeLa cancer cell line by 50%. N97: endophytic extracts from stem bark of Terminalia catappa; N169: endophytic extracts from twigs of Terminalia mantaly; N2: endophytic extracts from stem of Cananga odorata; N8: endophytic extracts from leaves of Cananga odorata; N233: endophytic extracts from leaves of Terminalia mantaly. NC: none converged.