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. 2020 Sep 16;5(38):24329–24339. doi: 10.1021/acsomega.0c02547

Figure 6.

Figure 6

Calibration curve of HDIT101 spiked in human plasma highlighting the response linearity over the concentration range from 20 to 5000 μg/mL (A). Representative MRM traces of HDIT101 surrogate peptide LC1 (B) and its IS SIL-LC1 (C) in a blank plasma sample (BV) and at LLOQ (20 μg/mL) and ULOQ (5000 μg/mL) levels. Absolute intensity of the most intense peak of each MRM trace is indicated on the baseline of each trace. The retention time of the targeted compounds is given in bold character on the top trace.