Table 3.
Median Intervention Outcomes
| Score, median [IQR] | ||||
|---|---|---|---|---|
| Measure | Baseline | Post-intervention | Change | p-value |
| 25FW (sec) | 9.1 [6.4–15.0] | 6.9 [4.9–10.9] | −1.8 [− 4.1–0.1] | – |
| 2MWT (m) | 94.8 [49.1–127.4] | 114.8 [94.3–153.5] | 23.8 [19.0–28.8] | – |
| MFIS | ||||
| Physical | 25.5 [25.0–28.5] | 22.5 [18.5–26.0] | −2.5 [− 6.3–1.5] | .317 |
| Cognitive | 21.0 [14.0–28.3] | 16.0 [11.3–22.3] | −4.0 [− 7.5 – − 1.3] | .058 |
| Psychosocial | 4.0 [2.3–5.0] | 4.5 [3.3–7.3] | 0.5 [0.0–1.8] | .256 |
| Total | 53.0 [48.3–59.5] | 45.0 [37.3–49.8] | −6.0 [− 11.0–1.5] | .317 |
| MSWS-12 | 44.0 [37–49.0] | 32 [29.3–39.8] | −10.5 [− 13.0 – − 2.5] | .057 |
| SPPB | ||||
| Balance | 3.0 [2.0–4.0] | 4.0 [3.3–4.0] | 0.0 [0.0–1.0] | .046 |
| Gait | 3.5 [1.3–4.0] | 4.0 [2.3–4.0] | 0.0 [0.0–1.0] | .046 |
| Chair Stand | 1.5 [1.0–2.8] | 3.5 [1.3–4.0] | 1.0 [0.3–1.8] | .008 |
| Total | 7.5 [5.5–9.8] | 10.5 [7.5–12.0] | 2.0 [1.3–2.8] | .002 |
IQR interquartile range, 25FW 25-ft walk test, 2MWT 2-min walk test, MFIS Modified Fatigue Impact Scale, MSWS-12 Multiple Sclerosis Walking Scale, SPPB Short Physical Performance Battery