Figure 5.

Effects of the ultrahigh dose of Au₂₅ clusters on pathology. (a) H&E staining results and (c) immunohistochemical analysis in the hippocampal CA1 and cortical M1 regions of the brain. No significant increase was observed in the number of (b) pyknosis neurons and (d) glial fibrillary acidic protein (GFAP) in the brain tissue of mice injected with Au₂₅ clusters at an ultrahigh dose. * indicates p > 0.05 as compared with the control group, ** indicates p < 0.05 as compared with the control mouse and the experimental mouse (data is analyzed by ANOVA).