Table 1.

Characteristics of the two-stage bIRI model

	Anesthetized Mean Arterial Pressure, mmHg	Body Weight, g	Right Kidney Weight, g	Left Kidney Weight, g
Two-stage bIRI 0-min group	89 ± 2.8	32.9 ± 1.5	0.170 ± 0.018	0.165 ± 0.015
Two-stage bIRI 15-min group	93 ± 3.1	33.1 ± 1.6	0.169 ± 0.021	0.161 ± 0.019
Two-stage bIRI 18-min group	91 ± 3.4	31.5 ± 1.9	0.152 ± 0.017	0.146 ± 0.020
Two-stage bIRI 21-min group	88 ± 2.7	29.2 ± 2.1	0.091 ± 0.024*	0.084 ± 0.021*
Two-stage bIRI 24-min group	90 ± 3.3	26.8 ± 1.7	0.079 ± 0.029*	0.060 ± 0.018*

Values are means ± SE. There was no significant difference in anesthetized mean arterial pressure among all groups at the end of experiments (n = 9–10 mice/group). Compared with the two-stage bilateral ischemia-reperfusion injury (bIRI) 0-min group, body weight and kidney weight were lower in the two-stage bIRI 21-min and two-stage bIRI 24-min groups but not significantly different in the two-stage bIRI 15-min or two-stage bIRI 18-min groups (n = 9 or 10 mice/group).

^*P < 0.001 vs. the two-stage bIRI 0-min group.