Table 3.
Show results of meta-analysis including pooled HR, 95% CI, sensitivity analysis, and publication bias
| Prognostic factors | N | HR range | Pooled HR | Pooled 95% CI | Heterogeneity (I2) | Model | p | Sensitivity analysis | Affected study | Publication bias (Egger’s test) |
|---|---|---|---|---|---|---|---|---|---|---|
| The male vs. the female [16, 29–31, 35] | 7 | 0.65–3.87 | 1.09 | 0.87–1.37 | 55.3% | Random | 0.466 | No effect | None | 0.556 |
| The older vs. the younger [14, 16, 29–32, 35, 37] | 9 | 0.63–8.13 | 1.45 | 0.98–2.16 | 80.3% | Random | 0.065 | Effect |
Yuan, Z. N. et al. [14], Hwang, I. K. et al. [37], Fan, Q. et al. [16], LaFemina, J. et al. [29] |
0.284 |
| NF 1 vs. non-NF 1 MPNST [11, 13–16, 18, 30, 34–37, 40, 42] | 13 | 1.00–3.54 | 1.56 | 1.35–1.79 | 34.1% | Fixed | 0.000 | No effect | None | 0.569 |
| Large size vs. small size [13, 14, 17, 28, 30, 31, 35–37, 44] | 10 | 1.04–7.88 | 1.93 | 1.62–2.29 | 44.4% | Random | 0.000 | No effect | None | 0.059 |
| Deep vs. superficial to fascia [14, 15, 24, 29, 34] | 5 | 1.79–3.16 | 2.09 | 1.52–2.89 | 0.0% | Fixed | 0.000 | No effect | None | 0.227 |
| Trunk vs. extremity [15, 17, 18, 24, 34] | 5 | 1.01–3.70 | 1.79 | 1.07–3.00 | 74.9% | Random | 0.025 | Effect | Stucky, C. C. et al. [40], Longhi, A. et al. [17], Anghileri, M. et al. [18] | 0.041 |
| Head and neck vs. extremity [14–16, 18, 30, 40] | 6 | 1.10–4.15 | 1.38 | 1.07–1.78 | 30.3% | Fixed | 0.014 | Effect | Valentin, T. et al. [15] | 0.047 |
| Grade II vs. Grade I [13–16, 31] | 6 | 0.89–2.99 | 1.43 | 1.06–1.91 | 43.7% | Fixed | 0.017 | Effect | Mowery, A. et al. [31], Miao, R. Y. et al. [13] | 0.126 |
| Grade III vs. Grade I [13–16, 31] | 6 | 0.89–35.88 | 3.21 | 1.36–7.54 | 86.9% | Random | 0.008 | No effect | None | 0.006 |
| With vs. without metastases [13, 16, 31, 32, 44] | 6 | 1.11–4.80 | 2.30 | 1.50–3.51 | 62.3% | Random | 0.000 | No effect | None | 0.359 |
| R1 vs. R0 resection [13, 15, 28, 30, 37] | 6 | 0.98–5.93 | 1.31 | 1.04–1.64 | 22.3% | Fixed | 0.022 | Effect | Ma, C. et al. [28] | 0.149 |
| R2 vs. R0 resection [13–15, 18, 28–30, 35, 37] | 10 | 0.97–13.15 | 2.40 | 1.96–2.95 | 0.0% | Fixed | 0.000 | No effect | None | 0.019 |
| With vs. without chemotherapy [14, 16, 18, 30, 32, 35, 40] | 7 | 0.38–0.99 | 0.70 | 0.59–0.83 | 6.3% | Fixed | 0.000 | No effect | None | 0.877 |
| With vs. without radiotherapy [14–16, 18, 28, 30, 35] | 7 | 0.31–0.96 | 0.65 | 0.49–0.88 | 50.0% | Random | 0.005 | No effect | None | 0.006 |