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Schematic of experimental design and metabolic testing protocol. B, vastus lateralis biopsy; BF, brachial artery blood flow; BS, blood sampling; CGM, continuous glucose monitoring; CON:CR, control/caloric restriction; CR, caloric restriction; DXA, dual-energy X-ray absorptiometry; EI, energy intake; eTRF, early time-restricted feeding; IC, indirect calorimetry; PA, physical activity.
