FIGURE 5.

Indices of whole-body insulin sensitivity: (A, B) arterialized blood glucose, (C) iAUC for glucose, (D, E) arterialized serum insulin, (F) iAUC for insulin, and (G) Matsuda index of insulin sensitivity in response to consumption of a liquid test meal before (pre) and after (post) 2 wk of dietary intervention. All data are means ± SEMs; n = 8 per group. P values displayed in text boxes refer to mixed-design 3-factor ANOVA (intervention group × pre-post trial × sampling time) performed for the entire postprandial period (A, B, D, and E) and mixed-design 2-factor ANOVA (intervention group × pre-post trial) performed for iAUC data (C, F). CON:CR, control/caloric restriction; eTRF, early time-restricted feeding; iAUC, incremental area under the curve; M-ISI, Matsuda index of insulin sensitivity.