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. 2020 Jul 30;112(4):1015–1028. doi: 10.1093/ajcn/nqaa192

TABLE 5.

Skeletal muscle analysis before (pre) and 2 wk after (post) eTRF1

Pre-eTRF Post-eTRF
Characteristic 0 min 180 min 0 min 180 min
BCAA, µmol·kgDW−1 2059 ± 150 1839 ± 122 1934 ± 132 2015 ± 171
KA, µmol·kgDW−1 56.4 ± 6.2 44.6 ± 8.3 58.0 ± 8.2 55.7 ± 12.0
Glycogen, mmol glycosyl units·kgDW−1 359 ± 25 360 ± 36 382 ± 48 380 ± 43
PDC activity, nmol·mg protein−1· min−1 4.17 ± 0.64 4.41 ± 0.61** 3.77 ± 0.34 5.42 ± 0.74**

1Data are means ± SEMs; n = 7. Mixed-design 2-factor ANOVA revealed no intervention or interaction effects for muscle BCAA (P = 0.89 and P = 0.10, respectively), KA (P = 0.53 and P = 0.37, respectively), glycogen (P = 0.57 and P = 0.96, respectively), or PDC (P = 0.69 and P = 0.30, respectively). A time effect (**P = 0.002 from respective 0 min) was observed for PDC only. BCAA, branched-chain amino acid (sum of leucine, isoleucine, and valine); DW, dry weight; eTRF, early time-restricted feeding; KA, branched-chain keto acids (sum of ketoisocaproic, 2-keto-3-methyl-valeric, and ketoisovaleric acids); PDC, pyruvate dehydrogenase complex.