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. 2020 Jul 20;112(4):956–966. doi: 10.1093/ajcn/nqaa181

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Copyright © The Author(s) on behalf of the American Society for Nutrition 2020.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Results from the mediation model of the association between PRS_BMI and obesity measures. Standardized regression coefficients (95% CIs) from the mediation model of the snacking behavior pattern. All models were adjusted for age, sex, and genetic principal components, and twin pair clustering was taken into account in all analyses. The indirect effect (or mediation effect) is represented by ab, and c represents the direct effect; total effect = c + ab. Ellipses represent latent factors and rectangles represent observed variables. n = 949 for BMI and n = 874 for WC. PRS_BMI, polygenic risk score for BMI; WC, waist circumference.