Table 3.
Nested case–control placental morphometry by third-trimester maternal serum 25 hydroxycholecalciferol levels.
| Variables | < 20 ng/mLN = 9 | >40 ng/mLN = 9 | P value |
|---|---|---|---|
| 25(OH)D 32-38 weeks’ gestation (ng/mL) | 11.43 (4.37) | 53.53 (12.56) | <.05 |
| Chorionic villi (surface density) | 0.056 (0.015) | 0.070 (0.0060) | .043 |
| Intermediate villi (volume density) | 0.14 (0.059) | 0.13 (0.059) | NS |
| Intervillous fibrinoid (volume density) | 0.045 (0.037) | 0.031 (0.014) | NS |
| Intervillous space (volume density) | 0.40 (0.059) | 0.38 (0.063) | NS |
| Stem villi (volume density) | 0.13 (0.034) | 0.12 (0.031) | NS |
| Terminal villi (volume density) | 0.28 (0.047) | 0.31 (0.037) | NS |
| Total villi (volume density) | 0.55 (0.066) | 0.58 (0.082) | NS |
| Villous fibrin (volume density) | 0.044 (0.037) | 0.045 (0.018) | NS |
| Villous trophoblast (volume density) | 0.070 (0.012) | 0.066 (0.0089) | NS |
| Villous capillaries (volume density) | 0.054 (0.028) | 0.052 (0.022) | NS |
| Villous capillaries (surface density) | 0.031 (0.013) | 0.035 (0.011) | NS |
| Villous stroma (volume density) | 0.37 (0.044) | 0.40 (0.089) | NS |
| Placental volume (mL) | 395 (53) | 501 (184) | NS |
| Placental weight (g) | 425 | 545 (145) | NS |
NS, not significant.