. 2020 Sep 17;11:572659. doi: 10.3389/fphar.2020.572659

Table 5.

The enzyme inhibitory activity of H. flavum rhizome EO, WE, and EE¹.

Samples	α-Glucosidase		Tyrosinase		Acetylcholinesterase		Butyrylcholinesterase
Samples	IC₅₀ (mg/mL)	(mmoL ACEs/g sample)	IC₅₀ (mg/mL)	(mg KAEs/g sample)	IC₅₀ (mg/mL)	(mg GALAEs/g sample)	IC₅₀ (mg/mL)	(mg GALAEs/g sample)
EO	4.15 ± 0.26^a	0.094 ± 0.002^a	6.12 ± 0.16^a	32.51 ± 0.82^a	4.84 ± 0.36^a	0.051 ± 0.007^a	23.66 ± 1.61^a	0.20 ± 0.01^a
WE	0.064 ± 0.004^b	6.02 ± 0.79^b	10.49 ± 1.48^b	19.30 ± 2.72^b	2.27 ± 0.13^b	0.108 ± 0.011^b	0.65 ± 0.04^b	7.24 ± 0.26^b
EE	0.19 ± 0.01^c	2.04 ± 0.20^c	9.62 ± 0.94^b	20.85 ± 1.12^b	5.93 ± 0.36^c	0.042 ± 0.005^a	16.64 ± 1.33^c	0.23 ± 0.02^a
Acarbose	0.25 ± 0.02^d
Kojic acid			0.20 ± 0.01^c
Galanthamine^*					0.25 ± 0.04^d		4.71 ± 0.15^d

¹C₅₀: The concentration of sample that affords a 50% inhibition in the assay. GALAEs, KAEs, and ACEs: galanthamine, kojic acid, and acarbose equivalents, respectively.

^a-dDifferent letters in the same column represent significant difference (p<0.05).

*Galanthamine: IC₅₀ (μg/mL).