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PTEN somatic mutations in human T-cell acute lymphoblastic leukemia (T-ALL) and solid tumors. (A) PTEN somatic mutations found in T-ALL. Data collected from Liu et al. (2017) and Seki et al. (2017) along with our unpublished results. (B) PTEN somatic mutations found in solid tumors. Data adapted from cBioPortal for Cancer Genomics. (DSPc) dual specificity phosphatase, catalytic domain (aa80–159), (PTEN_C2) C2 domain of PTEN tumor-suppressor protein (aa188–349).
