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PUL-042 treatment induces resistance against CoV pneumonia. (A) Survival of mice challenged with SARS-CoV. N = 20 mice/group. (B) Lung viral burden of mice 3 days after challenge with MERS-CoV. N = 5 mice/group. *P < 0.00001 versus sham treated. **P < 0.0001 versus sham treated. CoV = coronavirus; MERS-CoV = Middle East respiratory syndrome CoV; PFU = plaque-forming unit; SARS-CoV = severe acute respiratory syndrome CoV.
