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. 2020 Oct;63(4):436–443. doi: 10.1165/rcmb.2020-0034MA

Figure 4.

Figure 4.

EM of vesicle ultrastructure results for A549/ABCA3−/− cells that express ABCA3 WT, p.E292V, or p.L101P are similar to results from adenoviral transduced A549 and ATII cells. White arrows indicate normal-appearing lamellar body–like vesicles, and black arrows indicate abnormal-appearing lamellar body–like vesicles. Cells that express p.L101P demonstrate smaller, dark vesicles and few normal-appearing lamellar body–like vesicles in all three cell systems, whereas cells that express p.E292V have lamellar body–like vesicles similar to those of cells that express ABCA3 WT. Scale bar, 800 nm.