TABLE 2.
Association of serum Lp(a) concentrations with incident risk of reduced renal function
| Cases, n (%) | Model 1 | Model 2 | |||||
| OR | 95% CI | P | OR | 95% CI | P | ||
| Continuous | |||||||
| Log10-Lp(a) | 158 (2.5) | 1.81 | 1.08–3.01 | 0.02 | 1.99 | 1.15–3.43 | 0.01 |
| Categorical | |||||||
| Tertile 1 | 43 (2.1) | Reference | Reference | ||||
| Tertile 2 | 49 (2.4) | 1.11 | 0.72–1.73 | 0.62 | 1.21 | 0.76–1.92 | 0.41 |
| Tertile 3 | 66 (3.0) | 1.54 | 1.01–2.33 | 0.04 | 1.61 | 1.03–2.52 | 0.03 |
| P for trend | 0.03 | 0.03 | |||||
Data are OR and 95% CI. Model 1 was adjusted for sex, baseline age, and BMI; model 2 was further adjusted for baseline FPG, SBP, log10-TG, HDL-C, LDL-C, mildly decreased GFR, smoking and drinking status, and use of antihypertensive drugs and antidiabetic drugs.