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. 2020 Sep 21;16(9):e1008854. doi: 10.1371/journal.ppat.1008854

Fig 4. Analysis of recruited immune populations on day 1 and 3 post A. fumigatus challenge.

Fig 4

Freshly harvested conidia from the AF293 isolate were delivered via aerosolization (12 mL, 1 X 109 conidia/mL) to immuno-competent wild type and Nlrx1-/- mice. Recruited immune cell populations in (AB) bronchoalveolar lavage fluid BALF and (C-J) pulmonary tissue by wild type and Nlrx1-/- mice on day 1 and 3 post inoculation were determined by flow cytometry. Asterisk denotes statistical significance, P < 0.05 Mann-Whitney U test. Error bars indicate standard deviation. N = 8–10 per experimental group. AM, alveolar macrophages. IM, interstitial macrophages. DC, dendritic cells. pDC, plasmocytoid dendritic cells. moDC, monocytoid dendritic cells. cDC, conventional dendritic cells. NK, natural killer cells.