Fig 1. Principle of enhanced image formation via super-resolution generative adversarial network (SR-GAN).

A modified SR-GAN was used to learn the differences between the low-resolution optic-disc photography (ODP) and the manually compensated high-resolution ODP. By inputting the high-resolution original ODP into the algorithm, an X4 up-scaled and overall contrast-, color- and brightness-transformed ‘enhanced ODP’ could be obtained.