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. 2020 Oct 1;15(10):e0240027. doi: 10.1371/journal.pone.0240027

Table 3. Subgroup analysis stratified by independent variables*.

Variables HbA1c ≥5.7%
Sex-specific RHGSa
Q1 (low) Q2 (mid-low) Q3 (mid-high) Q4 (high) P value for trend
OR 95% CI OR 95% CI OR 95% CI OR
Male
Age (years)
 19–29 2.75 (0.70 - 10.83) 2.86 (0.90 - 9.11) 1.67 (0.42 - 6.57) 1.00 0.1143
 30–39 2.06 (1.13 - 3.75) 1.79 (1.02 - 3.14) 1.43 (0.83 - 2.46) 1.00 0.0340
 40–49 1.05 (0.60 - 1.82) 0.84 (0.53 - 1.34) 0.74 (0.46 - 1.19) 1.00 0.8438
 50–59 1.62 (0.97 - 2.72) 1.81 (1.13 - 2.89) 1.51 (0.97 - 2.35) 1.00 0.0439
 ≥60 1.02 (0.65 - 1.63) 0.94 (0.59 - 1.50) 0.94 (0.56 - 1.57) 1.00 0.8427
Smoking
 Yes 1.35 (1.02 - 1.79) 1.31 (1.01 - 1.69) 1.12 (0.86 - 1.46) 1.00 0.1243
 No 1.64 (0.91 - 2.94) 1.36 (0.77 - 2.40) 1.22 (0.71 - 2.10) 1.00 0.2343
Alcohol consumption
 Yes 1.50 (1.14 - 1.97) 1.43 (1.10 - 1.86) 1.22 (0.94 - 1.58) 1.00 0.0521
 No 0.98 (0.52 - 1.83) 0.81 (0.44 - 1.47) 0.84 (0.45 - 1.57) 1.00 0.9467
Practicing aerobic exercise
 Yes 1.81 (1.23 - 2.67) 1.88 (1.32 - 2.68) 1.49 (1.02 - 2.16) 1.00 0.0078
 No 1.17 (0.84 - 1.64) 1.00 (0.74 - 1.36) 0.96 (0.70 - 1.30) 1.00 0.7596
Obesity status (BMI)b
 Underweight and Normal range 1.06 (0.65 - 1.74) 0.92 (0.60 - 1.41) 1.10 (0.73 - 1.64) 1.00 0.6782
 Overweight 0.91 (0.58 - 1.43) 1.11 (0.72 - 1.71) 1.07 (0.71 - 1.61) 1.00 0.4073
 Obese 1.90 (1.23 - 2.92) 1.70 (1.12 - 2.60) 1.28 (0.82 - 1.99) 1.00 0.0034
Waist circumferencec
 Men(≥90cm), Women(≥85cm) 2.40 (1.52 - 3.80) 2.00 (1.26 - 3.17) 1.76 (1.11 - 2.81) 1.00 0.0026
 Men(<90cm), Women(<85cm) 1.01 (0.74 - 1.38) 1.14 (0.85 - 1.52) 1.03 (0.77 - 1.36) 1.00 0.4977
Female
Age (years)
 19–29 0.63 (0.31 - 2.00) 1.38 (0.51 - 3.74) 0.20 (0.01 - 0.75) 1.00 0.9819
 30–39 0.97 (0.45 - 2.06) 0.81 (0.42 - 1.56) 0.71 (0.41 - 1.23) 1.00 0.9816
 40–49 1.42 (0.89 - 2.25) 0.76 (0.49 - 1.19) 0.83 (0.57 - 1.22) 1.00 0.3440
 50–59 0.96 (0.62 - 1.48) 1.06 (0.72 - 1.55) 1.07 (0.75 - 1.53) 1.00 0.7479
 ≥60 1.09 (0.64 - 1.86) 0.89 (0.53 - 1.51) 1.21 (0.73 - 2.02) 1.00 0.9589
Smoking
 Yes 1.48 (0.72 - 3.03) 0.86 (0.42 - 1.74) 0.80 (0.44 - 1.47) 1.00 0.6348
 No 1.10 (0.85 - 1.43) 0.97 (0.77 - 1.24) 1.01 (0.82 - 1.26) 1.00 0.7534
Alcohol consumption
 Yes 1.16 (0.86 - 1.58) 0.92 (0.70 - 1.21) 0.97 (0.76 - 1.23) 1.00 0.6670
 No 1.03 (0.70 - 1.51) 0.99 (0.67 - 1.47) 0.99 (0.67 - 1.47) 1.00 0.9589
Practicing aerobic exercise
 Yes 1.17 (0.80 - 1.70) 0.87 (0.64 - 1.19) 0.97 (0.72 - 1.31) 1.00 0.7674
 No 1.07 (0.77 - 1.49) 1.01 (0.74 - 1.39) 0.98 (0.74 - 1.29) 1.00 0.8685
Obesity status (BMI)b
 Underweight and Normal range 1.01 (0.72 - 1.41) 0.91 (0.67 - 1.23) 0.99 (0.78 - 1.26) 1.00 0.5765
 Overweight 0.99 (0.60 - 1.63) 0.90 (0.56 - 1.44) 0.84 (0.52 - 1.35) 1.00 0.8835
 Obese 1.03 (0.55 - 1.95) 0.82 (0.44 - 1.54) 0.84 (0.44 - 1.61) 1.00 0.3574
Waist circumferencec
 Men(≥90cm), Women(≥85cm) 0.81 (0.44 - 1.51) 0.69 (0.37 - 1.30) 0.67 (0.36 - 1.27) 1.00 0.7709
 Men(<90cm), Women(<85cm) 1.07 (0.81 - 1.41) 0.94 (0.73 - 1.21) 0.97 (0.78 - 1.21) 1.00 0.8557

*Adjusted for age, marital status, region, household income, job, educational status, smoking status, alcohol consumption, practicing aerobic exercise, BMI, waist circumference, and the number of chronic diseases.

a Relative Hand Grip Strength, categorized into sex-specific quartiles

Men: Q1(<2.78), Q2(2.78–3.22), Q3(3.22–3.66), Q4(>3.66) / Women: Q1(<1.67), Q2(1.67–2.00), Q3(2.00–2.33), Q4(>2.33).

bBMI: Body mass index; obesity status was defined by BMI based on the 2018 Clinical Practice Guidelines for Overweight and Obesity in Korea.

cCentral obesity is defined using waist circumference. The cut-off points for Korean adults were decided by the Korean Society for the Study of Obesity.