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. 2020 Sep 7;11(10):2975–2982. doi: 10.1111/1759-7714.13653

Figure 6.

Figure 6

Relationship between miR200b expression and the PD‐L1 TPS in driver mutation‐negative lung cancer patients. (a) miR200b expression in human cancer cells collected via bronchoscopy was detected using RT‐qPCR. PD‐L1 expression was assessed immunohistochemically, and the patients were divided into two groups with high (<50%) and low (≥50%) PD‐L1 expression. The P‐values were determined using the Mann‐Whitney U test. (b) The correlation between miR200b expression and the PD‐L1 TPS was evaluated using Pearson's correlation coefficients. (c) miR200b expression in serum‐derived exosomes was detected using RT‐qPCR, whereas PD‐L1 expression was assessed immunohistochemically (<50% vs. ≥50%). (d) The correlation between miR200b expression in serum‐derived exosomes and the PD‐L1 TPS is shown. (e) The correlation between miR200b expression in lung cancer tissue and miR200b expression in serum‐derived exosomes is shown. The P‐values were determined using the Mann‐Whitney U test, and the correlations were analyzed using Pearson's correlation coefficients.