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. 2020 Sep 3;11(10):2987–2992. doi: 10.1111/1759-7714.13628

Table 3.

Multivariate analysis for association between EGF+61 genotype and alleles from TKI‐treated NSCLC patients harboring EGFR‐sensitizing mutations (n = 111) and TKI treatment response

Response to TkI treatment* n OR 95% CI P‐value
Codominant model PR AA 23 1 Ref.
AG 42 0.50 0.09–2.80 0.43
GG 13 0.39 0.05–2.62 0.33
SD AA 10 1 Ref.
AG 4 0.08 0.01–0.60 0.01
GG 4 0.19 0.02–1.58 0.12
Recessive model PR AA 23 1 Ref.
AG + GG 55 0.47 0.91–2.44 0.37
SD AA 10 1 Ref.
AG + GG 8 0.12 0.20–0.72 0.02

Bold P‐values indicate P ≤ 0.05 from multivariate analysis by multinomial adjusted by age, TNM and PS‐ECOG. Reference category: DP, disease progression.

PR, partial response; SD, stable disease; Ref., reference category.

*According to RECIST criteria.