Table 1.
Most significant lab findings, including thrombophilia screening
General biological findings |
Coagulation workup | Thrombophilia screening and complement evaluation |
||
---|---|---|---|---|
At admission | Most abnormal value (d) | During the hospital stay | ||
Leucocyte count | 8.84 G/L | 14.7 G/L (D10) | Antithrombine (N 83-125) | 94% |
Lymphocyte count | 0.59 G/L | 0.41 G/L (D9) | C protein (N 70-140) | 137% |
Platelet count | 248 G/L | 108 G/L (D4) | S protein (N 74-146) | 88% |
Hemoglobin | 14.3 g/dL | 7.3 g/dL (D11) | Antiphospholids antibodies | |
Fibrinogen | 9.3 g/l | / | IgM anticardiolpines (N < 20) | 12.4 U/mL |
D-dimer | 4169 ng/mL | / | IgG anticardiolpines (N < 20) | 5.8 U/mL |
Factor V | 118% | / | IgM/ antiBeta2 GP1 (N < 20) | 8.0 UI/mL |
Albumin | 23 g/L | 21 g/L (D8) | IgG antiBeta2 GP1 (N < 20) | 3.1 UI/mL |
Bilirubin | 2 μmol/L | 7 μmol/L (D8) | Lupus anticoagulant | 2 negative tests∗ |
eGFR (CKD-EPI) | 85 ml/min/1.73 m2 | 50 (D10) | Mutation for factor II and V | Negative |
AST ALT |
48 UI/L 43 UI/L |
175 (D8) 174 (D11) |
Homocysteinemia (N 3.2 to 10.7 μmol/l) | 10 μmol/L |
NT-proBNP | 1319 pg/mL | C3 (N 0.85-1.8) | 1.40 g/L | |
Troponine Ic | <0.015 ng/mL | C4 (N 0.13-0.39) | 0.10 g/L | |
LDH (N [57-241]) | 391 UI/L | CH50 U/mL (N 31.7-71.4) | 53.8 U/mL |
ALT, alanine aminotransferase; AST, aspartate aminotransferase; CKD-EPI, chronic kidney disease epidemiology collaboration; eGFR, estimated glomerular filtration rate; Ig, immunoglobulin; LDH, lactic acid dehydrogenase; NT pro BNP, N-terminal pro brain natriuretic peptide.
Compliant with the International Society of Thrombosis and Hemostasis (ISTH) guidelines.