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. 2020 Jun 15;382(1):5–14. doi: 10.1007/s00441-020-03224-7

Fig. 2.

Fig. 2

Rapid TrkB surface translocation upon EGF stimulation of cortical precursor cells. Time course of pTrk-PLCγ activation after EGF stimulation in cortical precursor cells (a–g: pTrk-PLCγ-IR; a′–g′: merged images). Immediately after the EGF pulse, after less than 2s (b, b′), the signal for pTrk-PLCγ appears first intracellularly and subsequently at the cell membrane after 10s (d/d–-g/g′). Bar: 3 μm. Figure reproduced with permission from Puehringer et al. Nature Neurosci. 2013