Figure 2.

Forest plot of p values by gene and study. This plot presents the p values from the single-nucleotide polymorphism (SNP)–based meta-analysis, organized by study and gene of interest. The magenta line is set at a threshold of p = .160, which is considered suggestive as corresponding to the Akaike information criterion (AIC). The points at the p value of 1.0 are those that were set conservatively at 1.0 in studies that did not provide a p value (i.e., reported only that results were “not significant”). It is noted that due to the novelty of combining various numbers of measured SNPs across genes and studies, this forest plot is presents p values and not effect sizes, as is standard practice.