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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: Clin Gastroenterol Hepatol. 2020 Mar 30;19(2):349–357. doi: 10.1016/j.cgh.2020.03.047

Table 3.

Genetic Mutations in Patients with EO-ICP, LO-ICP, Light to Moderate Drinking with CP, and ACP

Light to Moderate
Mutation EO-ICP (n=61) LO-ICP (n=69) Drinker with CP (n=308) ACP (n=225) P Value (Overall) P Value (EO-ICP vs LO-ICP)
Any, No. (%) 30 (49) 16 (23) 79 (26) 51 (23) <.001 .004
SPINK1, No. (%) 15 (24) 6 (9) 22 (7) 21 (9) <.003 .03
CTRC, No. (%) 2 (3) 2 (3) 3 (1) 3 (1) .83 ≥99
CFTR, No. (%) 22 (36) 10 (15) 59 (19) 30 (13) .001 .008

Abbreviations: ACP, alcohol-related chronic pancreatitis; CP, chronic pancreatitis; EO-ICP, early-onset idiopathic chronic pancreatitis; LO-ICP, late-onset idiopathic chronic pancreatitis.