Table 4.
Age at Onset of Pancreatitis By Mutation Status in Patients with EO-ICP, LO-ICP, Light to Moderate Drinking with CP, and ACP
| Mutation | EO-ICP (n=61) | LO-ICP (n=69) | Light to Moderate Drinking with CP (n=308) | ACP (n=225) |
|---|---|---|---|---|
| Any, y, median (IQR) | ||||
| Yes | 19.5 (8–23) | 54.5 (45.5–67) | 39 (25–52)a | 44 (36–49) |
| No | 20 (16–29) | 58 (47–67) | 51 (40–63) | 44 (36–53) |
| SPINK1, y, median (IQR) | ||||
| Yes | 12 (8–20) | 54 (45–67) | 24 (20–36)a | 39 (28–44) |
| No | 22 (16.5–29)b | 58 (46–67) | 50 (38–62) | 45 (36–52) |
| CTRC, y, median (IQR) | ||||
| Yes | 15.5 (4–27) | 51.5 (42–61) | 42 (39–45) | 40 (39–48) |
| No | 20 (12–27) | 58 (46–67) | 47(35–61) | 44 (36–52) |
| CFTR, y, median (IQR) | ||||
| Yes | 21 (8–27) | 47 (45–67) | 41 (28–55)c | 46.5 (41–51) |
| No | 19 (13–27) | 59 (47–67) | 50 (37–62) | 43.5 (35.5–52) |
Abbreviations: ACP, alcohol-related chronic pancreatitis; CP, chronic pancreatitis; EO-ICP, early-onset idiopathic chronic pancreatitis; LO-ICP, late-onset idiopathic chronic pancreatitis; Q1, first quartile; Q3, third quartile.
a
P<.001.
b
P=.004.
c
P=.03.