. Author manuscript; available in PMC: 2022 Jan 1.

Published in final edited form as: Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 Apr 2;6(1):70–78. doi: 10.1016/j.bpsc.2020.03.006

Table 4.

Longitudinal Mixed-Effect Models of annualized change in NPI total score explained by whole brain WMH load, age, sex, education and baseline total NPI scores.

	Estimate	SE	tStat	pValue
Intercept	−0.017	0.044	−0.394	0.693
Age	−0.002	0.035	−0.069	0.945
Sex	0.069	0.066	1.039	0.299
Education	0.022	0.031	0.705	0.481
WMH	0.085	0.035	2.454	0.014^**
NPI total Baseline	0.629	0.033	19.204	9.8252E-68

^**

denotes statistical significance, ◇Denotes a trend; one-tailed test p<0.1