Fig 1:

A) Stenosis with a severity of 77% area reduction at the mid-portion of the SVG. B) Virtual removal of the stenosis to obtain pre-diseased state. C) Anatomic parameters computed from 3D models reconstructed from patients’ CTA data. D) Schematic view of a multi-scale patient-specific model of the coronary circulation, coupling a closed-loop lumped parameter network (LPN) to a 3D model. The LPN parameters, such as resistances and capacitances, were tuned to match clinical targets to within 10%.