Table 1.
Demographic findings and Tumor, Node, Metastasis (TNM) staging according to genetic mutation type.
| ROS1 | EGFR | ALK | P-value | ||
|---|---|---|---|---|---|
| ROS1 vs EGFR | ROS1 vs ALK | ||||
| No. of patients | 23 | 120 | 26 | ||
| Age, years* | 56 (31–76) | 62 (28–83) | 56 (30–83) | 0.006 | 0.882 |
| Sex | 0.273 | 0.319 | |||
| M | 5 (22) | 40 (33) | 9 (35) | ||
| F | 18 (78) | 80 (66) | 17 (65) | ||
| Smoking | 0.076 | 0.885 | |||
| Never | 17 (74) | 79 (66) | 20 (77) | ||
| Ex-smoker | 4 (17) | 39 (33) | 5 (19) | ||
| Current | 2 (9) | 2 (2) | 1 (4) | ||
| Pack years* | 4 (0–25) | 6 (0–40) | 2 (0–30) | ||
| T stage | 0.380 | 0.060 | |||
| T1 | 8 (35) | 25 (21) | 6 (23) | ||
| T2 | 9 (39) | 56 (47) | 6 (23) | ||
| T3 | 1 (4) | 16 (13) | 9 (35) | ||
| T4 | 5 (22) | 23 (19) | 5 (19) | ||
| N stage | 0.047 | 0.803 | |||
| N0 | 2 (9) | 39 (33) | 5 (19) | ||
| N1 | 1 (4) | 8 (7) | 1 (4) | ||
| N2 | 4 (17) | 24 (20) | 4 (15) | ||
| N3 | 16 (70) | 49 (41) | 16 (62) | ||
| M stage | 0.042 | 0.159 | |||
| 0 | 2 (9) | 2 (2) | 0 | ||
| 1a | 8 (35) | 25 (21) | 6 (23) | ||
| 1b | 13 (57) | 93 (78) | 20 (77) | ||
Unless otherwise indicated, data are presented as number of patients with the percentage in parentheses.
*Data are presented as the median with the range in parentheses.