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. 2020 Oct 1;10:16251. doi: 10.1038/s41598-020-73533-y

Table 3.

Univariate and multivariate analyses for significant predictors of ROS1-rearranged adenocarcinomas.

Variables Univariable analysis Multivariable analysis*
HR (95% CI) P-value HR (95% CI) P-value
Size 0.99 (0.97, 1.01) 0.244
Age 1.04 (1.01, 1.08) 0.026 1.06 (1.01, 1.12) 0.024
Location 0.84 (0.34, 2.06) 0.191
Air-bronchogram 0.25 (0.07, 0.87) 0.030 0.34 (0.01, 1.43) 0.142
Calcification 4.55 (0.59, 35.32) 0.148
Pleural retraction 0.48 (0.20, 1.16) 0.102
Central low-attenuation 0.89 (0.34, 2.32) 0.820
Pleural metastasis 0.61 (0.25, 1.49) 0.278
Pericardial metastasis 15.60 (4.10, 58.81)  < 0.001 10.50 (2.10, 52.60) 0.005
Bone metastasis 0.53 (0.19, 1.52) 0.234
Nodal metastasis 5.46 (1.23, 24.52) 0.025 8.55 (1.14, 62.52) 0.037
Pleural effusion 2.53 (1.04, 6.17) 0.041 2.63 (0.81, 8.55) 0.107

HR hazard ratio, CI confidence interval.

*P-values < 0.1 in the univariate analysis were involved in the multivariate analysis.