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. 2020 Oct 1;11:4928. doi: 10.1038/s41467-020-18638-8

Table 1.

vPECA model component and notations.

Data and variables Notations Examples
Individual and time-dependent data
Expression of TF TFi,j,m: = expression of the mth TF of individual i on time j TFW1,1,EPAS1 = 23.87
Expression of TG, not TF TGi,j,l: = expression of the lth TG of individual i on time j TGW1,1,NQO1 = 97.35
Accessibility of RE Oi,j,k: = openness of the kth RE of individual i on time j OW1,1,chr2:46589710-46594828, = 1.14
Individual and time dependent latent variable
Activation status of a RE Zi,j,k: = activation status of the kth RE of the ith individual on time j ZW1,1,chr2:46574334-46580523 = 2.72
Population dependent data
FST score Xp,1: = FST score of pth SNP Xrs3768729,1 = 4.62
iHS score Xp,2: = iHS score of pth SNP Xrs3768729,2 = 9
XP-EHH score Xp,3: = XP-EHH score of pth SNP Xrs3768729,3 = 1.94
PBS score Xp,4: = PBS score of pth SNP Xrs3768729,4 = 4.94
Weight of the pth SNP wp: = weight of the pth SNP derived from LD score wrs3768729 = 0.0583
TFs with motif on a RE MBk: = set of TFs with motif match in kth RE ARNT has motif match at chr2:46589710-46594828
Individual dependent data
The difference of Derived Allele Frequencies between two populations ΔDAF Yp: = ΔDAF of pth SNP Yrs3768729 = −0.8
Motif matching strength of TF on RE Bi,k,m: = matching strength of the mth TF binding on the kth RE of individual i BW1,chr2:46589710-46594828,BACH1 = 2.90
Population and individual dependent latent variables
Selection status of a RE Sk: = selection status of the kth RE Schr2:46589710-46594828 = 1