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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: J Cell Physiol. 2020 Apr 24;235(11):8520–8532. doi: 10.1002/jcp.29696

Figure 3.

Figure 3.

Cancellous bone microarchitecture assessed by μCT of vertebral body of Lumbar 3 (L3) from 1 (upper panels) and 4 (lower panels) month old BGLAP-Cre;Nfatc1Δ/Δ;Nfatc2Δ/Δ female mice (black bars) and sex-matched littermate Nfatc1loxP/loxP;Nfatc2loxP/loxP controls (white bars). Parameters shown are: bone volume/tissue volume (BV/TV); connectivity density (Conn.D); structure model index (SMI); trabecular number (Tb.N) and trabecular thickness (Tb.Th). Values are means ± SD; n = 5 for control and n = 8 for Nfatc1Δ/Δ;Nfatc2Δ/Δ mice. A representative image shows cancellous bone osteopenia in 4 month old BGLAP-Cre;Nfatc1Δ/Δ;Nfatc2Δ/Δ female mice.