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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: J Pharmacokinet Pharmacodyn. 2020 Jun 4;47(5):385–409. doi: 10.1007/s10928-020-09691-3

Fig. 7.

Fig. 7

Correlation of estimated model parameters versus mAb PPC metric at CDR vicinity. (a) Positive association between estimated Spino value and mAb PPC metric: Spino = 0.89+0.72·PPC (R2=0.53, p = 0.0013, residual standard error = 0.256). (b) No significant association between estimated Sdiff-conv value and mAb (p = 0.18). (c) Positive correlation between estimated CLLymCapSC and mAb PPC metric: CLLymCapSC=0.51+2.13PPC (R2=0.74, p=0.00036, residual standard error=0.539). (d) No significant association between estimated SLymUptSC and mAb PPC metric (p = 0.549)