Fig. 9.

Model-predicted and digitized concentration versus time profiles for Tildrakizumab for each dose. Filled dots indicate digitized Tildrakizumab PK profiles from literature, after single SC dose of (a) 50 mg, (b) 200 mg. Solid lines show the predicted median. Dash lines indicate the predicted 5^th and 95^th percentiles. The shaded areas display the 5^th to 95^th percentile population simulation regions