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Summary table of activity counts measured during nicotine CPP test. JZL184 does not alter locomotor activity on test day compared to vehicle. Data are expressed as mean ± S.E.M. of 6 – 8 mice/group.
| CPP Activity Counts (sec) | ||
|---|---|---|
| Saline | Nicotine (0.5 mg/kg) | |
| V ehicle | 1321 ± 177 | 1380 ± 122 |
| JZL184 (16 mg/kg) | 1338 ± 140 | 1232 ± 92 |
| JZL184 (24 mg/kg) | 1104 ± 199 | 1234 ± 127 |
| JZL184 (40 mg/kg) | 893 ± 168 | 1075 ± 58 |
