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. Author manuscript; available in PMC: 2021 Mar 11.
Published in final edited form as: Arch Pathol Lab Med. 2021 Jan 1;145(1):46–54. doi: 10.5858/arpa.2019-0398-OA

Table 2.

Summary of Mismatch Repair (MMR) Immunoperoxidase Results in Cytology Effusion Specimens and Concordance With Surgical Pathology Specimens

Case Cancer
Type
No. of
Tumor Cells
MMR IPOX Cell Block
MMR IPOX/
MSI-PCR Surgical
Concordant
MLH1 PMS2 MSH2 MSH6
1 CRC <10 R R R R Intact Yes
2 CRC <10 R R R R Intact Yes
3 CRC 10–50 R R R R Intact Yes
4 CRC 10–50 R R R R Intact Yes
5 CRC 10–50 R R R R Intact Yes
6 EC 10–50 R R L L L MSH2/6 Yes
7 CRC 10–50 R R R R Intact Yes
8 CRC 10–50 R R R R Intact Yes
9 EC 10–50 R R R R Intact Yes
10 CRC 10–50 R R R R Intact Yes
11 CRC 51–300 R R R R Intact Yes
12 CRC 51–300 R R R R Intact Yes
13 CRC 51–300 R R R R Intact Yes
14 CRC 51–300 R R R R Intact Yes
15 CRC 51–300 R R R R Intact Yes
16 CRC 51–300 R R R R Intact Yes
17 EC 51–300 R R R R Intact Yes
18 CRC 51–300 R R R R Intact Yes
19 CRC 51–300 R R R R Intact Yes
20 CRC 51–300 R R R R Intact Yes
21 CRC 51–300 R R R R Intact Yes
22 CRC 51–300 R R R R Intact Yes
23 CRC 51–300 R R R R Intact Yes
24 CRC 51–300 R R R R Intact Yes
25 CRC 51–300 R R R R Intact Yes
26 CRC 51–300 R R R R Intact Yes
27 CRC 51–300 R R R R Intact Yes
28 CRC >300 R R R R Intact Yes
29 CRC >300 R R R R Intact Yes
30 CRC >300 R R R R Intact Yes
31 CRC >300 R R R R Intact Yes
32 CRC >300 R R R R Intact Yes
33 CRC >300 R R R R Intact Yes
34 EC >300 R R R R Intact Yes
35 CRC >300 R R R R Intact Yes
36 CRC >300 R R R R Intact Yes
37 CRC >300 R R R R Intact Yes
38 CRC >300 R R R R Intact Yes
39 CRC >300 R R R R Intact Yes
40 CRC >300 R R R R Intact Yes
41 CRC >300 R R R R Intact Yes
42 EC >300 R R R R Intact Yes
43 EC >300 R R R R Intact Yes
44 CRC >300 R R R R Intact Yes
45 CRC >300 R R R R Intact Yes
46 CRC 10–50 R R R S-CIFT Intact Inconclusive
47 EC 10–50 S-CIFT R R NC Intact Inconclusive
48 CRC 10–50 R R R S-QS Intact Inconclusive
49 CRC 51–300 R R S-CIFT L L MSH2/6 Inconclusive
50 CRC 51–300 R R R S-CIFT Intact Inconclusive
51 CRC 51–300 R R R NC Intact Inconclusive
52 CRC 51–300 R R R L Intact No
53 CRC 51–300 S-QS L R R Intact No

Abbreviations: CRC, colorectal carcinoma; EC, endometrial carcinoma; IPOX, immunoperoxidase; L, lost; MSI, microsatellite instability; NC, noncontributory; PCR, polymerase chain reaction; R, retained; S-CIFT, suboptimal–focal staining of cells indefinite for tumor; S-QS, suboptimal–tumor with questionable staining.