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. 2020 Oct 1;10:16223. doi: 10.1038/s41598-020-72876-w

Figure 4.

Figure 4

(A,B) Fragments of the brain sections containing the motor cortex (Animal 02/100 Gy, pictures are taken from the same brain section). (A) non-irradiated hemisphere, normal tissue appearance; (B) irradiated hemisphere, visible numerous cells with condensed chromatin indicating possible cell physiology changes caused by radiation; (C) blood vessels dilatation and thickening (arrows) near the irradiated areas. Section from the minipig A04/80 Gy, Nissl&Eosin; (D) glial scar surrounding necrosis (GFAP positive astroglia); (E) A04/80 Gy brain sections stained N&E; arrows point to areas with fibrous tissue, arrowheads points to blood vessels. *amorphic, eosinophilic substance (caseous necrosis); n—necrosis (liquefactive necrosis), with numerous white blood cells visible; < —red blood cells in the tissue; (F) glial scar (arrows) surrounding the necrosis (N).