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. Author manuscript; available in PMC: 2021 Jan 26.
Published in final edited form as: Int J Obes (Lond). 2020 Jul 26;44(10):2011–2022. doi: 10.1038/s41366-020-0644-1

Figure 2.

Figure 2.

Association of pre-treatment brain response to a meal with change in BMI z-score, behavioral, and hormonal outcomes by FBT. Reduction in brain activation by high-calorie (A, B), but not low-calorie (C), food cues in response to a standardized meal (post-pre meal activation) predicted greater reduction in BMI z-score during FBT. Change in brain activation by high-calorie food (vs. object) images in response to a standardized meal (post-pre meal) was associated with FBT-induced changes Health Eating Index scores from 3 24-hr food records (D), but was unrelated to FBT-induced changes in physical activity by actigraphy (E), plasma leptin (F), and HOMA-IR (G). Physical activity includes moderate and vigorous, healthy eating index was determined based on 2010 criteria. P-value by linear regression, Pearson’s correlation coefficients calculated for descriptive purposes.