Table 1.

Participant characteristics for key behavioral and hormonal measures.

	Pre-Treatment			Post-Treatment			P-value	Change
	Mean	SD	N	Mean	SD	N		Mean	SD	N
Height, cm	148	8.2	37	151	8.3	37	<0.0001	3.38	0.96	37
Weight, kg	65.2	18.4	37	64.3	20.1	37	0.29	−0.89	5.14	37
BMI, kg/m2	29.5	7.0	37	28.1	7.6	37	<0.0001	−1.47	2.18	37
BMI z-score	2.24	0.31	37	2.01	0.44	37	<0.0001	−0.23	0.23	37
BMI % over the 95th	28.5	28.7	37	19.5	30.9	37	<0.0001	−9.01	9.26	37
Fat mass, kg	31.6	14.2	37	30.6	16.2	35	0.06	−1.29	4.07	35
Fat mass, %	48.1	6.8	37	45.3	8.5	35	<0.0001	−2.81	3.50	35
Lean mass, kg	32.4	5.2	37	34.0	5.6	35	<0.0001	1.55	1.69	35
Lean mass, %	51.9	6.8	37	54.7	8.5	35	<0.0001	2.81	3.50	35
Waist circumference, cm	96.1	14.1	37	95.8	16.5	37	0.77	−0.28	5.75	37
Activity, avg min/d	35.8	21.4	37	38.1	23.8	35	0.55	2.37	23.8	35
Healthy Eating Index	54.1	12.0	37	60.8	12.4	34	0.008	6.07	14.4	34
Leptin, ng/mL	34.1	22.0	35	27.3	19.6	35	0.007	−7.43	15.5	33
HOMA-IR	3.95	3.75	33	4.56	3.62	34	0.28	0.69	3.41	30

Data reported as mean (SD). Pre-treatment vs. Post-treatment comparisons are unadjusted and were done by linear mixed model. Height, weight and BMI parameters measured at Week 1 and Week 24 of FBT. All other measures were assessed at pre-treatment and post-treatment study visits. BMI parameters were calculated with LMS values by sex and age and BMI % over the 95^th was calculated as the percent the current BMI was over the estimated 95% BMI percentile (https://www.cdc.gov/growthcharts/percentile_data_files.htm). Body composition parameters were by bioelectrical impedance analysis. Activity is moderate and vigorous levels (average min/d from 7 days of consecutive wear). Healthy Eating Index calculated based on 2010 criteria.