Table 1.

Demographic and clinical characteristics by methamphetamine (METH) group

	METH−	METH+
Variable	(n=47)	(n=75)	P
Demographics
Age (years), mean (SD)	40.0 (10.04)	39.8 (7.44)	0.914
Education (years), mean (SD)	13.0 (1.92)	12.9 (2.16)	0.759
Estimated premorbid verbal IQ, mean (SD)	99.4 (12.00)	97.2 (12.52)	0.355
Race/Ethnicity Non-Hispanic White, n (%)	28 (59.6%)	52 (68.4%)	0.395
Hispanic, n (%)	8 (17.4%)	12 (16.0%)
Black, n (%)	10 (21.7%)	8 (10.7%)
Other, n (%)	1 (2.2%)	2 (2.7%)
Neuropsychiatric Characteristics
Lifetime Major Depressive Disorder, n (%)^a	25 (54.4%)	36 (52.9%)	0.883
BDI-II score, median [IQR]	7 [2, 13]	15 [8, 21]	<0.001
Antidepressant use, n (%)	16 (34.0%)	28 (37.3%)	0.712
Lifetime alcohol use disorder, n (%)^a	24 (52.2%)	52 (76.5%)	0.007
Current alcohol use disorder, n (%)^b	2 (4.4%)	0 (0.0%)	0.158
Lifetime cannabis use disorder, n (%)^a	14 (30.4%)	36 (52.9%)	0.017
Current cannabis use disorder, n (%)^b	1 (2.2%)	1 (1.5%)	0.773
Lifetime cocaine use disorder, n (%)^a	6 (13.0%)	27 (39.7%)	0.001
Medical Characteristics
Hepatitis C virus seropositive, n (%)	5 (10.6%)	24 (32.0%)	0.031
HIV seropositive, n (%)	30 (63.8%)	50 (66.7%)	0.825
AIDS diagnosis, n (%)	17 (56.7%)	24 (48.0%)	0.452
Duration of HIV infection (years), median [IQR]	9.1 [1.5, 12.0]	6.9 [2.9, 12.7]	0.824
Current CD4 count (cells/mm³), median [IQR]	470 [349, 653]	401 [297, 675]	0.228
Nadir CD4 count (cells/mm³), median [IQR]	201 [56, 324]	218 [58, 381]	0.676
Detectable plasma viral load, n (%)	11 (36.7%)	30 (62.5%)	0.026
On ART, n (%)	21 (72.4%)	33 (66.0%)	0.552
Methamphetamine Use Parameters
Lifetime days of use	-	1503 [669, 3611]	-
Lifetime grams consumed	-	1357 [408, 2825]	-
Lifetime average daily use (grams/day)	-	0.77 [0.38, 1.25]	-
Days since last use	-	61 [16, 122]	-
Age of first use	-	23.3 (7.62)	-

ART= antiretroviral therapy; BDI-II= Beck Depression Inventory- II;

N = 117;

N = 115