Figure 2:

R² Decomposition resulting from regressions of the Social Hallmarks of Aging and Multiple Biological Measures on Four Age-Related Health Outcomes: Model 1 – the Social Hallmarks, Model 2 biological Measures, Model 3 both sets of measures, Model 4 adding Polygenic risk

A. Model 1 – R² attributed to Social Hallmarks and Demographc Factors

B. Model 2 – R² attributed to Biological and Demographic Factors

C. Model 3 - R² attributed to Biological, Demographic, and Social Factors

D. Model 4: Non-Hispanic White Only - R² attributed to Genetic, Biological, Demographic, and Social Factors

Models 1–3 (N=1159); Model 4 (N=832)

Decomposed R² shown in supplemental table 1