MRI of participant 8, showing diffuse white matter lesion in the right temporal lobe, and a necrotic area in the temporal pole, affecting both white and gray matter (study MRI, right). A substantial radiation dose has been delivered to the area (original treatment plan, left). The dose is shown in Gray, the red being areas with higher dose. The patient was enucleated following radiotherapy. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)