Table 2B.
Demographic, clinical, cognitive, functioning profiles of “Better” and “Poorer” clusters.
| Variables | HC & Baseline FEPa | HC & Follow-Up FEPb | Baseline & Follow-Up FEPc | |||
|---|---|---|---|---|---|---|
| Cluster 1: Better functioning (N = 16) | Cluster 2: Poorer functioning (N = 37) | Cluster 1: Better functioning (N = 40) | Cluster 2: Poorer functioning (N = 11) | Cluster 1: Better functioning (N = 27) | Cluster 2: Poorer functioning (N = 11) | |
| Patients (count, %) |
5 (31.25%) |
15 (40.54%) | 12 (30.00%) | 6 (54.55%) |
N/A | N/A |
| Schizophrenia (count, %) |
N/A | N/A | N/A | N/A |
8
(29.63%) |
8
(72.73%) |
| Age | 24.44 (4.6) |
22.14 (4.6) |
23.08 (3.8) |
23.09 (3.8) |
22.67 (3.0) |
23.91 (3.0) |
| Females (count, %) |
6 (37.50%) |
13 (35.14%) | 14 (35.00%) | 4 (36.36%) |
10 (37.04%) | 3 (27.27%) |
| Education (years) |
16.31
(1.8) |
14.89
(1.8) |
15.38 (1.7) |
15.36 (1.7) |
14.89 (1.2) |
15.27 (1.2) |
| UPSA | 80.99 (9.8) |
82.59 (9.8) |
83.57 (9.0) |
81.07 (9.0) |
81.2 (12.8) |
81.44 (12.8) |
| MCAS | 52.21 (4.3) |
51.88 (4.3) |
52.94
(4.3) |
49.22
(4.3) |
49.33 (7.3) |
44.6 (7.3) |
| MCAS Independent Subscore | 9.75 (0.8) |
9.31 (0.8) |
9.5
(1.3) |
8.0
(1.3) |
8.61
(2.1) |
6.78
(2.1) |
| MCAS Social Subscore |
18.94 (2.0) |
18.83 (2.0) |
19.39
(1.6) |
17.88
(1.6) |
17.91
(3.4) |
15.56
(3.4) |
| MATRICS Social Subscore | 54.5 (8.7) |
54.03 (8.7) |
55.41 (8.2) |
52.0 (8.2) |
57.0
(14.2) |
45.75
(14.2) |
| MATRICS Neurocognitive Composite Score |
50.3 (5.1) |
48.27 (5.1) |
50.66
(5.0) |
46.78
(5.0) |
48.11 (9.3) |
44.52 (9.3) |
| TASIT | 55.25 (6.0) |
54.87 (6.0) |
56.03
(4.3) |
52.62
(4.3) |
54.87 (6.5) |
52.12 (6.5) |
| PANSS Positive | N/A | N/A | N/A | N/A | 13.33 (6.2) |
15.3 (6.2) |
| PANSS Negative | N/A | N/A | N/A | N/A | 11.15 (3.6) |
12.6 (3.6) |
| PANSS General | N/A | N/A | N/A | N/A | 27.81 (7.2) |
31.5 (7.2) |
| PANSS Total | N/A | N/A | N/A | N/A | 52.3 (15.6) |
59.4 (15.6) |
Note 1: means with standard deviations in parentheses. Note 2: Higher values indicate better functioning in UPSA/MCAS/MCAS-Independent/MCAS-Social/MATRICS-Social/MATRICS Neurocognitive/TASIT measures. Higher values indicate more symptomatic in PANSS Positive/PANSS Negative/PANSS General/PANSS Total measures. Note 3: aBaseline measures for both HC and FEP subjects were used; bBaseline measures were used for HC and follow-up measures were used for patients; cBaseline measures were used for baseline patients and follow-up measures were used for follow-up patients. Note 4: Significant difference between the two cluster means (p-value < 0.05) was shown in bold.