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. 2020 Sep 30;39(3):259–268. doi: 10.23876/j.krcp.20.053

Table 3.

Medical management of acute kidney injury following cardiac surgery

Treatment Mechanism Action in kidney
Furosemide Na+, K+, 2Cl- symporter (NKCC2) antagonist Diuresis
Fenoldopam D1 receptor antagonist Renal vasodilation and increased blood flow
Theophylline & aminophylline (xanthine derivatives) Inhibit adenosine-induced vasoconstriction Increased renal blood flow, diuresis