Table 4.
Phase II genes. Genes that were not detected by RNA‐seq or omitted due to extremely low counts during edgeR process are shown as blank.
| EnsemblID | Symbol | Description | Log FC | Log CPM | FDR | ||
|---|---|---|---|---|---|---|---|
| Perfused/2D | Nonperfused/2D | Perfused/Nonperfused | |||||
| ENSG00000148344 | PTGES | Prostaglandin E synthase | 4.70 | 5.06 | −0.37 | 4.83 | 2.99E‐07 |
| ENSG00000172482 | AGXT | Alanine‐glyoxylate aminotransferase | 4.32 | 3.98 | 0.34 | 2.76 | 2.16E‐06 |
| ENSG00000088002 | SULT2B1 | Sulfotransferase family, cytosolic, 2B, member 1 | 3.17 | 2.97 | 0.20 | −0.49 | 1.27E‐03 |
| ENSG00000166741 | NNMT | Nicotinamide N‐methyltransferase | 2.25 | 3.23 | −0.98 | 6.73 | 5.00E‐08 |
| ENSG00000198203 | SULT1C2 | Sulfotransferase family, cytosolic, 1C, member 2 | 1.71 | 2.47 | −0.76 | 1.88 | 4.77E‐05 |
| ENSG00000124713 | GNMT | Glycine‐N‐methyltransferase | 1.67 | 1.63 | 0.04 | −0.01 | 1.08E‐02 |
| ENSG00000198075 | SULT1C4 | Sulfotransferase family, cytosolic, 1C, member 4 | 1.65 | 1.53 | 0.12 | 2.75 | 9.40E‐05 |
| ENSG00000187210 | GCNT1 | Glucosaminyl (N‐acetyl) transferase 1, core 2 | 1.42 | −0.13 | 1.55 | 3.40 | 8.53E‐05 |
| ENSG00000130066 | SAT1 | Spermidine/spermine N1‐acetyltransferase 1 | 1.39 | 0.30 | 1.08 | 8.29 | 1.11E‐05 |
| ENSG00000172828 | CES3 | Carboxylesterase 3 | 1.35 | 1.10 | 0.25 | 3.66 | 4.72E‐05 |
| ENSG00000136881 | BAAT | Bile acid CoA: amino acid N‐acyltransferase (glycine‐N‐choloyltransferase) | 1.31 | 0.91 | 0.41 | 5.05 | 4.02E‐05 |
| ENSG00000135220 | UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | 1.12 | 1.09 | 0.02 | 0.79 | 8.30E‐02 |
| ENSG00000148154 | UGCG | UDP/glucose ceramide glucosyltransferase | 1.08 | 0.33 | 0.76 | 5.45 | 3.57E‐06 |
| ENSG00000213366 | GSTM2 | Glutathione S‐transferase mu 2 (muscle) | 0.99 | 2.03 | −1.04 | 3.76 | 6.29E‐07 |
| ENSG00000005187 | ACSM3 | Acyl‐CoA synthetase medium‐chain family member 3 | 0.91 | 1.55 | −0.64 | 3.61 | 4.27E‐05 |
| ENSG00000131446 | MGAT1 | Mannosyl (alpha‐1,3‐)‐glycoprotein beta‐1,2‐N‐acetylglucosaminyltransferase | 0.89 | 0.54 | 0.35 | 7.30 | 8.62E‐05 |
| ENSG00000151726 | ACSL1 | Acyl‐CoA synthetase long‐chain family member 1 | 0.85 | 1.37 | −0.53 | 6.10 | 1.08E‐06 |
| ENSG00000123983 | ACSL3 | Acyl‐CoA synthetase long‐chain family member 3 | 0.76 | 0.23 | 0.53 | 6.27 | 1.10E‐05 |
| ENSG00000105398 | SULT2A1 | Sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)‐preferring, member 1 | 0.54 | −1.76 | 2.31 | −0.81 | 9.08E‐02 |
| ENSG00000141744 | PNMT | Phenylethanolamine N‐methyltransferase | 0.48 | 0.39 | 0.09 | 0.42 | 4.40E‐01 |
| ENSG00000143198 | MGST3 | Microsomal glutathione S‐transferase 3 | 0.18 | 0.48 | −0.29 | 5.43 | 1.42E‐03 |
| ENSG00000257594 | GALNT4 | UDP‐N‐acetyl‐alpha‐D‐galactosamine:polypeptide N‐acetylgalactosaminyltransferase 4 (GalNAc‐T4) | 0.13 | 1.29 | −1.16 | 4.68 | 1.72E‐04 |
| ENSG00000066813 | ACSM2B | Acyl‐CoA synthetase medium‐chain family member 2B | 0.06 | 0.36 | −0.31 | −1.06 | 8.29E‐01 |
| ENSG00000093010 | COMT | Catechol‐O‐methyltransferase | 0.04 | 0.03 | 0.02 | 6.52 | 8.30E‐01 |
| ENSG00000134202 | GSTM3 | Glutathione S‐transferase mu 3 (brain) | −0.02 | 0.03 | −0.05 | 5.25 | 8.42E‐01 |
| ENSG00000128311 | TST | Thiosulfate sulfurtransferase (rhodanese) | −0.03 | 0.17 | −0.20 | 4.75 | 1.47E‐01 |
| ENSG00000068366 | ACSL4 | Acyl‐CoA synthetase long‐chain family member 4 | −0.04 | −0.51 | 0.47 | 7.15 | 1.03E‐04 |
| ENSG00000085871 | MGST2 | Microsomal glutathione S‐transferase 2 | −0.07 | −0.12 | 0.05 | 5.31 | 5.11E‐01 |
| ENSG00000172831 | CES2 | Carboxylesterase 2 | −0.10 | 0.27 | −0.37 | 4.85 | 3.06E‐02 |
| ENSG00000196433 | ASMT | Acetylserotonin O‐methyltransferase | −0.14 | −0.93 | 0.79 | −0.61 | 3.20E‐01 |
| ENSG00000065621 | GSTO2 | Glutathione S‐transferase omega 2 | −0.31 | −0.29 | −0.02 | 4.28 | 3.15E‐02 |
| ENSG00000197448 | GSTK1 | Glutathione S‐transferase kappa 1 | −0.33 | −0.11 | −0.21 | 5.83 | 6.86E‐03 |
| ENSG00000168765 | GSTM4 | Glutathione S‐transferase mu 4 | −0.33 | −0.14 | −0.19 | 3.96 | 1.21E‐01 |
| ENSG00000084207 | GSTP1 | Glutathione S‐transferase pi 1 | −0.35 | −0.45 | 0.09 | 6.00 | 5.48E‐03 |
| ENSG00000085998 | POMGNT1 | Protein O‐linked mannose beta1,2‐N‐acetylglucosaminyltransferase | −0.38 | −0.01 | −0.37 | 5.86 | 1.85E‐03 |
| ENSG00000130005 | GAMT | Guanidinoacetate N‐methyltransferase | −0.39 | −0.20 | −0.19 | 5.00 | 1.27E‐02 |
| ENSG00000150540 | HNMT | Histamine N‐methyltransferase | −0.46 | −0.30 | −0.17 | 5.56 | 2.70E‐02 |
| ENSG00000244038 | DDOST | Dolichyl‐diphosphooligosaccharide‐‐protein glycosyltransferase | −0.47 | −0.49 | 0.03 | 9.26 | 2.97E‐04 |
| ENSG00000196502 | SULT1A1 | Sulfotransferase family, cytosolic, 1A, phenol‐preferring, member 1 | −0.49 | −0.26 | −0.23 | 5.97 | 1.74E‐02 |
| ENSG00000147119 | CHST7 | Carbohydrate (N‐acetylglucosamine 6‐O) sulfotransferase 7 | −0.54 | −0.55 | 0.01 | 1.64 | 1.57E‐01 |
| ENSG00000120915 | EPHX2 | Epoxide hydrolase 2, cytoplasmic | −0.56 | −0.31 | −0.25 | 3.49 | 4.53E‐02 |
| ENSG00000143819 | EPHX1 | Epoxide hydrolase 1, microsomal (xenobiotic) | −0.62 | −0.14 | −0.47 | 5.03 | 1.12E‐03 |
| ENSG00000197165 | SULT1A2 | Sulfotransferase family, cytosolic, 1A, phenol‐preferring, member 2 | −0.71 | −0.17 | −0.53 | 3.00 | 7.07E‐02 |
| ENSG00000170899 | GSTA4 | Glutathione S‐transferase alpha 4 | −0.81 | −0.33 | −0.47 | 4.42 | 6.07E‐04 |
| ENSG00000148834 | GSTO1 | Glutathione S‐transferase omega 1 | −0.83 | −0.69 | −0.14 | 6.90 | 3.80E‐06 |
| ENSG00000214435 | AS3MT | Arsenic (+3 oxidation state) methyltransferase | −0.92 | −0.40 | −0.52 | 3.95 | 1.33E‐03 |
| ENSG00000171234 | UGT2B7 | UDP glucuronosyltransferase 2 family, polypeptide B7 | −1.02 | 0.15 | −1.17 | 2.23 | 2.21E‐03 |
| ENSG00000173418 | NAA20 | N(alpha)‐acetyltransferase 20, NatB catalytic subunit | −1.02 | −0.96 | −0.07 | 5.59 | 3.12E‐06 |
| ENSG00000141429 | GALNT1 | UDP‐N‐acetyl‐alpha‐D‐galactosamine:polypeptide N‐acetylgalactosaminyltransferase 1 (GalNAc‐T1) | −1.03 | −1.17 | 0.14 | 6.68 | 5.70E‐07 |
| ENSG00000008394 | MGST1 | Microsomal glutathione S‐transferase 1 | −1.13 | −0.49 | −0.64 | 6.33 | 1.33E‐06 |
| ENSG00000124588 | NQO2 | NAD(P)H dehydrogenase, quinone 2 | −1.17 | −0.70 | −0.47 | 4.87 | 3.92E‐06 |
| ENSG00000181019 | NQO1 | NAD(P)H dehydrogenase, quinone 1 | −1.27 | −0.70 | −0.56 | 7.46 | 2.89E‐05 |
| ENSG00000137364 | TPMT | Thiopurine S‐methyltransferase | −1.28 | −1.14 | −0.14 | 4.65 | 3.83E‐06 |
| ENSG00000168282 | MGAT2 | Mannosyl (alpha‐1,6‐)‐glycoprotein beta‐1,2‐N‐acetylglucosaminyltransferase | −1.31 | −1.49 | 0.18 | 4.68 | 8.21E‐07 |
| ENSG00000171428 | NAT1 | N‐acetyltransferase 1 (arylamine N‐acetyltransferase) | −1.65 | −0.87 | −0.78 | 1.49 | 8.77E‐03 |
| ENSG00000243955 | GSTA1 | Glutathione S‐transferase alpha 1 | −2.08 | −2.29 | 0.21 | −1.31 | 1.19E‐02 |
| ENSG00000173597 | SULT1B1 | Sulfotransferase family, cytosolic, 1B, member 1 | −4.93 | −5.69 | 0.76 | 3.47 | 1.05E‐08 |
| ENSG00000109193 | SULT1E1 | Sulfotransferase family 1E, estrogen‐preferring, member 1 | −9.13 | −9.13 | 0.00 | 0.57 | 2.27E‐05 |
| ENSG00000129673 | AANAT | Aralkylamine N‐acetyltransferase | |||||
| ENSG00000166743 | ACSM1 | Acyl‐CoA synthetase medium‐chain family member 1 | |||||
| ENSG00000171097 | CCBL1 | Cysteine conjugate‐beta lyase, cytoplasmic | |||||
| ENSG00000198848 | CES1 | Carboxylesterase 1 | |||||
| ENSG00000159398 | CES5A | Carboxylesterase 5A | |||||
| ENSG00000149124 | GLYAT | Glycine‐N‐acyltransferase | |||||
| ENSG00000174156 | GSTA3 | Glutathione S‐transferase alpha 3 | |||||
| ENSG00000182793 | GSTA5 | Glutathione S‐transferase alpha 5 | |||||
| ENSG00000134201 | GSTM5 | Glutathione S‐transferase mu 5 | |||||
| ENSG00000277656 | GSTT1 | Glutathione S‐transferase theta 1 | |||||
| ENSG00000241644 | INMT | Indolethylamine N‐methyltransferase | |||||
| ENSG00000156006 | NAT2 | N‐acetyltransferase 2 (arylamine N‐acetyltransferase) | |||||
| ENSG00000196228 | SULT1C3 | Sulfotransferase family, cytosolic, 1C, member 3 | |||||
| ENSG00000130540 | SULT4A1 | Sulfotransferase family 4A, member 1 | |||||
| ENSG00000138068 | SULT6B1 | Sulfotransferase family, cytosolic, 6B, member 1 | |||||
| ENSG00000241635 | UGT1A1 | UDP glucuronosyltransferase 1 family, polypeptide A1 | |||||
| ENSG00000244474 | UGT1A4 | UDP glucuronosyltransferase 1 family, polypeptide A4 | |||||
| ENSG00000241119 | UGT1A9 | UDP glucuronosyltransferase 1 family, polypeptide A9 | |||||
| ENSG00000173610 | UGT2A1 | UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus | |||||
| ENSG00000109181 | UGT2B10 | UDP glucuronosyltransferase 2 family, polypeptide B10 | |||||
| ENSG00000197888 | UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | |||||
| ENSG00000135226 | UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | |||||
| ENSG00000156096 | UGT2B4 | UDP glucuronosyltransferase 2 family, polypeptide B4 | |||||
| ENSG00000145626 | UGT3A1 | UDP glycosyltransferase 3 family, polypeptide A1 | |||||
| ENSG00000174607 | UGT8 | UDP glycosyltransferase 8 | |||||