Table 1.
Fibroblast lines used in RLS studies.
| Fibroblasts | Origin | References |
|---|---|---|
| 2BS | Human fetal lung diploid fibroblasts human, female | [58] |
| FB0603 | Human diploid foreskin fibroblasts | [47] |
| H8F2p 25LM fibroblasts | Isolated from human ear | [73] |
| HDFs | Human dermal fibroblasts | [8, 56, 60–62, 74] |
| HE49 | Human embryonic fibroblasts, normal | [37] |
| HEFs | Human embryonic fibroblasts, established from an abortus | [35] |
| HFF1 (ATCC® SCRC1041™) | Human foreskin, from a newborn male | [48, 66] |
| HFL1 (ATCC® CCL-153™) | Isolated from human fetal lungs, Caucasian | [57] |
| HGPS | Normal human skin fibroblast | [72] |
| Hs68 (ATCC® CRL-1635™) | Human skin (foreskin), from a newborn male, Caucasian | [46] |
| IMR-90 (ATCC® CCL-186™) | Human lung, female, 16 weeks of gestation, Caucasian | [12, 22, 30, 71] |
| MRC-5 (ATCC® CCL-171™) | Human lung, 14 weeks of gestation fetus, male, Caucasian | [44, 66, 75] |
| Normal diploid fibroblasts | Isolated from foreskin | [25, 26, 59] |
| Normal human skin fibroblasts | [64] | |
| NYaKe | Normal human adult fibroblasts derived from a 23-year-old healthy male | [27] |
| Primary cultures of human dermal fibroblasts | Female | [65] |
| WI-38 (ATCC® CCL-75™) | Human fetal lung diploid fibroblasts, 3 months of gestation fetus, female, Caucasian | [33, 34, 54, 55, 58, 76] |
| WS3RGB | Fibroblasts obtained from a 42-year-old female Werner syndrome patient | [37] |