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. 2020 May 18;37(10):2875–2886. doi: 10.1093/molbev/msaa125

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© The Author(s) 2020. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Fig. 2. — Positive correlations between tumor suppressor gene and oncogene copy numbers in 63 mammalian genomes. (A) PGLS regression between copy numbers of all tumor suppressor genes and copy numbers of oncogenes in mammalian genomes. (B) PGLS between copy numbers of caretaker genes and copy numbers of oncogenes. (C) PGLS between copy numbers of gatekeeper genes and copy numbers of oncogenes. Colors represent mammalian clades following figure 1A. All y axes are given in terms of normalized cancer gene copy number (the total number of cancer gene homologs divided by the number of found cancer gene orthologs). FDR: false discovery rate.