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. 2020 Oct 1;10:16261. doi: 10.1038/s41598-020-72328-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Process performance for a different HCV genotype. Shown is (A) the recovery of virus, DNA and protein during SXC and (B) the recovery of virus and DNA in the different SCMA fractions. Furthermore, (C) the total protein amounts and (D) the total DNA amounts throughout the process are depicted. All recovery values are step-recoveries, correlated to the quantities in the loading sample of the respective step. For the SCMA, no protein and DNA recoveries and amounts are depicted in case the concentration was below the limit of detection of the assay (0.5 µg/mL and 25 pg/mL for protein and DNA, respectively). Error bars indicate technical triplicates with error bars reflecting SD.