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. 2020 Jul 13;14(10):2646–2659. doi: 10.1002/1878-0261.12745

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© 2020 The Authors. Published by FEBS Press and John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Fig. 5 — The positive rate of EV‐LINC00853 in all‐stage and early‐stage HCC. (A) The rate of positive results of AFP and EV‐LINC00853 in patients with each liver disease status. The cutoff for positivity was defined as a 14‐fold increase in EV‐LINC00853 expression, and 20 ng·mL⁻¹ for AFP level. (B) The rate of positive results for EV‐LINC00853 by AFP status in patients with HCC. (C) The rate of positive results for EV‐LINC00853 by AFP status in patients with mUICC I/II. (D) The rate of positive results for EV‐LINC00853 by AFP status in patients with mUICC I. Target gene expression was calculated relative to that of HMBS.